Do you need a permit?
Where, precisely, do you go in order to get permission to make a dent in the universe?
The accepted state is to be a cog. The preferred career is to follow the well-worn path, to read the instructions, to do what we're told. It's safer that way. Less responsibility. More people to blame.
When someone comes along and says, "not me, I'm going down a different path," we flinch. We're not organized to encourage and celebrate the unproven striver. It's safer to tear them down (with their best interests at heart, of course). Better, we think, to let them down easy, to encourage them to take a safer path, to be realistic, to hear it from us rather than the marketplace.
Perhaps, years ago, this was good advice. Today, it's clearly not. In fact, it's disrespectful, ill-advised and short sighted. How dare we cheer when a bold changemaker stumbles? Our obligation today isn't to spare the feelings of our peers from future disappointment. It's to establish an expectation that of course they're going to do something that matters.
If you think there's a chance you can make a dent, GO.
You have my permission. Not that you needed it.